WWP1 Monoklonaler Antikörper

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• KD/KO Validated

WWP1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2G8G11

Kat-Nr. : 67804-1-PBS

Synonyme

2G8G11, AIP5, Atrophin-1-interacting protein 5, EC:2.3.2.26, HECT-type E3 ubiquitin transferase WWP1

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  WB analysis using 67804-1-Ig (same clone as 67804-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67804-1-Ig (WWP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Lamin B1 Monoclonal antibody (HRP-66095) as loading control. This data was developed using the same antibody clone with 67804-1-PBS in a different storage buffer formulation.

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  WB analysis of HaCaT using 67804-1-Ig (same clone as 67804-1-PBS)

  HaCaT cells were subjected to SDS PAGE followed by western blot with 67804-1-Ig (WWP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67804-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67804-1-PBS bindet in WB, Indirect ELISA WWP1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: WWP1 fusion protein Ag30171
• Vollständiger Name: WW domain containing E3 ubiquitin protein ligase 1
• Berechnetes Molekulargewicht: 922 aa, 105 kDa
• Beobachtetes Molekulargewicht: 95-105 kDa
• GenBank-Zugangsnummer: BC036065
• Gene symbol: WWP1
• Gene ID (NCBI): 11059
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

WW domain-containing E3 ubiquitin protein ligase 1 (WWP1) is a multifunction protein containing an N-terminal C2 domain, four tandem WW domains for substrate binding, and a C-terminal catalytic HECT domain for ubiquitin transferring. It is also named as AIP5, Tiul1. WWP1 regulates a variety of cellular biological processes including protein trafficking and degradation, signaling, transcription, and viral budding. WWP1 has been implicated in several diseases, such as cancers, infectious diseases, neurological diseases, and aging(PMID:22051607). It has 6 isoforms produced by alternative splicing.