• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

XBP1S-specific Rekombinanter Antikörper

XBP1S-specific Rekombinant Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, ELISA

Konjugation

Unkonjugiert

CloneNo.

241004C10

Kat-Nr. : 83959-6-PBS

Synonyme

XBP1, 241004C10, Tax-responsive element-binding protein 5, TREB-5, X box binding protein 1

Filter:
  • Immunohistochemistry (IHC) staining of mouse liver tissue using XBP1S-specific Recombinant antibody (83959-6-RR)

    IHC staining of mouse liver using 83959-6-RR (same clone as 83959-6-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83959-6-RR (XBP1S-specific antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83959-6-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using XBP1S-specific Recombinant antibody (83959-6-RR)

    IHC staining of mouse liver using 83959-6-RR (same clone as 83959-6-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83959-6-RR (XBP1S-specific antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83959-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83959-6-RR

    Affinity and Kinetic Characterization of 83959-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83959-6-RR against Human XBP1S-specific were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

83959-6-PBS bindet in IHC, ELISA XBP1S-specific und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen XBP1S-specific fusion protein Ag21703
Vollständiger Name X-box binding protein 1
Berechnetes Molekulargewicht 261 aa, 29 kDa
GenBank-ZugangsnummerBC000938
Gene symbol XBP1
Gene ID (NCBI) 7494
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

XBP1, also named as XBP2, belongs to the bZIP family. The X-box-binding protein-1 (XBP1) is a transcriptional regulator of the ER stress response that lies downstream of inositol-requiring enzyme 1 (IRE1α) activation (PMID: 14559994). XBP1 localizes in the nucleus. As a transcription factor, it is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The unspliced XBP1U isoform is composed of 261 amino acid residues, and the spliced XBP1S isoform is composed of 376 amino acid residues.