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YKT6 Polyklonaler Antikörper

YKT6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33685-1-PBS

Synonyme

EC:2.3.1.-, Synaptobrevin homolog YKT6, YKT6 V-SNARE Homolog

Filter:
  • Western Blot (WB) analysis of various lysates using YKT6 Polyclonal antibody (33685-1-AP)

    WB analysis using 33685-1-AP (same clone as 33685-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 33685-1-AP (YKT6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33685-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33685-1-PBS bindet in WB, Indirect ELISA YKT6 und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen YKT6 fusion protein Ag38740
Vollständiger Name YKT6 v-SNARE homolog (S. cerevisiae)
Berechnetes Molekulargewicht 22 kDa
Beobachtetes Molekulargewicht25 kDa
GenBank-ZugangsnummerBC007319
Gene symbol YKT6
Gene ID (NCBI) 10652
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

YKT6 is a soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) that plays a central role in membrane fusion in eukaryotic cells. It is primarily localized in the cytoplasm and, through its unique dual lipidation modification (palmitoylation and farnesylation), can associate with various organelle membranes, such as the Golgi apparatus, endosomes, and vesicles. By forming stable trans-SNARE complexes with other SNARE proteins (e.g., Syntaxin and SNAP-25 family members) on target membranes, YKT6 provides the driving force for membrane fusion, thereby facilitating intracellular trafficking. This protein is essential for maintaining organelle integrity, autophagy, and secretory pathways. Studies have shown that dysfunction of YKT6 is associated with various diseases, including cancer, neurodegenerative disorders, and metabolic abnormalities, making it a potential target for drug development.