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ZBTB17 Polyklonaler Antikörper

ZBTB17 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

Konjugation

Unkonjugiert

Kat-Nr. : 22691-1-PBS

Synonyme

MIZ 1, MIZ1, pHZ 67, Zinc finger protein 151, Zinc finger protein 60

Filter:
  • Western Blot (WB) analysis of various lysates using ZBTB17 Polyclonal antibody (22691-1-AP)

    WB analysis using 22691-1-AP (same clone as 22691-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22691-1-AP (ZBTB17 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22691-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using ZBTB17 Polyclonal antibody (22691-1-AP)

    WB analysis using 22691-1-AP (same clone as 22691-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22691-1-AP (ZBTB17 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22691-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22691-1-PBS bindet in ZBTB17 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZBTB17 fusion protein Ag18396
Vollständiger Name zinc finger and BTB domain containing 17
Berechnetes Molekulargewicht 803 aa, 88 kDa
Beobachtetes Molekulargewicht88-100 kDa
GenBank-ZugangsnummerBC126163
Gene symbol ZBTB17
Gene ID (NCBI) 7709
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-affinitätsgereinigt
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZBTB17 (zinc finger and BTB domain protein 17), also known as MIZ1, is a highly conserved transcription factor in evolution. It is expressed in many cell types and plays an important role in many biological processes such as cell cycle regulation, immune cell development and metabolic regulation. ZBTB17 plays a key role in the early stage of T cell development. It ensures the normal development of T cells by regulating the expression of pre-TCR and inhibiting the activity of TP53. ZBTB17 plays an important role in cardiac stress response, and its absence may lead to cardiomyopathy and heart failure. At Lys-397 and Lys-481, it undergoes "Lys-48" linked ubiquitination, and then degrades proteasome in a TRAF2-dependent manner.