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ZCCHC2 Polyklonaler Antikörper

ZCCHC2 Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25741-1-PBS

Synonyme

KIAA1744, C18orf49

Filter:
  • Immunoprecipitation (IP) experiment of HeLa cells using ZCCHC2 Polyclonal antibody (25741-1-AP)

    IP experiment of HeLa using 25741-1-AP (same clone as 25741-1-PBS)

    IP result of anti-ZCCHC2 (IP:25741-1-AP, 4ug; Detection:25741-1-AP 1:500) with HeLa cells lysate 1800 ug. This data was developed using the same antibody clone with 25741-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25741-1-PBS bindet in IP, Indirect ELISA ZCCHC2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZCCHC2 fusion protein Ag22744
Vollständiger Name zinc finger, CCHC domain containing 2
Berechnetes Molekulargewicht 1178 aa, 126 kDa
Beobachtetes Molekulargewicht150 kDa
GenBank-ZugangsnummerBC006340
Gene symbol ZCCHC2
Gene ID (NCBI) 54877
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZCCHC2 is a poorly characterized protein of 126 kDa with long intrinsically disordered regions, a PX domain, and a CCHC-type zinc-finger (ZnF) domain. ZCCHC2 is distantly related to ZCCHC14 but lacks the SAM domain that is known to interact with the CNGGN pentaloop in 1E and PRE. ZCCHC2 is a critical host factor for K5. ZCCHC2 recruits the terminal nucleotidyl transferase TENT4 to elongate poly(A) tails with mixed sequences, delaying deadenylation. The observed molecular weight is consistent with what has been described in the literature (PMID: 37413987).