ZFP42 Polyklonaler Antikörper

ZFP42 Polyklonal Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31790-1-AP

Synonyme

hREX-1, Reduced expression protein 1, REX1, REX-1, Zfp-42

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  WB analysis using 31790-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 31790-1-AP (ZFP42 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HL-60-Zellen, LNCaP-Zellen, PC-3-Zellen, Raji-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

31790-1-AP bindet in WB, ELISA ZFP42 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ZFP42 fusion protein Ag36112
• Vollständiger Name: zinc finger protein 42 homolog (mouse)
• Beobachtetes Molekulargewicht: 47 kDa
• GenBank-Zugangsnummer: BC160056
• Gene symbol: ZFP42
• Gene ID (NCBI): 132625
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The ZFP42, also known as REX1, is a transcriptional regulator and a member of the zinc finger protein family. It is specifically highly expressed in pluripotent stem cells, such as embryonic stem cells, and is one of the key molecules for maintaining cell pluripotency and self-renewal capacity. Its expression level rapidly declines with cell differentiation, making it widely used as a reliable marker for the pluripotent state. Studies have shown that ZFP42 is involved in inhibiting differentiation programs and maintaining stemness by regulating the transcription of downstream target genes. Additionally, its abnormal expression in various tumors suggests that it may be involved in tumorigenesis and development, making it an important subject in the research of regenerative medicine, developmental biology, and oncology.