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ZFP64 Polyklonaler Antikörper

ZFP64 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17187-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse spleen tissue using ZFP64 Polyclonal antibody (17187-1-AP)

    WB analysis of mouse spleen using 17187-1-AP (same clone as 17187-1-PBS)

    mouse spleen tissue were subjected to SDS PAGE followed by western blot with 17187-1-AP (ZFP64 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17187-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using ZFP64 Polyclonal antibody (17187-1-AP)

    WB analysis of HEK-293 using 17187-1-AP (same clone as 17187-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 17187-1-AP (ZFP64 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17187-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17187-1-PBS bindet in WB, Indirect ELISA ZFP64 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZFP64 fusion protein Ag10971
Vollständiger Name zinc finger protein 64 homolog (mouse)
Berechnetes Molekulargewicht 681 aa, 75 kDa
Beobachtetes Molekulargewicht 70 kDa
GenBank-ZugangsnummerBC041622
Gene symbol ZFP64
Gene ID (NCBI) 55734
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZFP64 (also known as ZNF338) is a member of the Krüppel C2H2-type zinc finger family. ZFP64 is a coactivator of Notch1, mediating mesenchymal cell differentiation. ZFP64 expression was up-regulated in mouse peritoneal macrophages in response to stimulation with the TLR4 ligand LPS with a 2-fold increase. The MLL gene encoding the MLL fusion protein is easily activated by ZFP64. ZFP64 is essential for the continuous production of MLL fusion proteins in blood cancer and produces more cancer cells. Since ZFP64 deletion completely and specifically inhibits MLL fusion protein production and leukemia cascade growth, it is an ideal drug target.