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SARA Polyklonaler Antikörper

SARA Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(4)

Kat-Nr. : 14821-1-AP

Synonyme

hSARA, Madh interacting protein, MADHIP, Novel serine protease, NSP, Receptor activation anchor, SARA, SMADIP, ZFYVE9



Geprüfte Anwendungen

Produktinformation

14821-1-AP bindet in WB, IF, ELISA SARA und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
In Publikationen genannte Reaktivitäthuman, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SARA fusion protein Ag6592
Vollständiger Name zinc finger, FYVE domain containing 9
Berechnetes Molekulargewicht 1425 aa, 156 kDa
GenBank-ZugangsnummerBC032680
Gene symbol SARA
Gene ID (NCBI) 9372
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZFYVE9, also known as SARA (Smad anchor for receptor activation), is a double zinc finger (FYVE domain) protein that interacts directly with SMAD2 and SMAD3, and is involved in Alzheimer's disease. SARA functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. SARA plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. SARA is possibly associated with TGF-beta receptor internalization.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for SARA antibody 14821-1-APProtokoll herunterladen
STANDARD-PROTOKOLLE
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Publikationen

SpeciesApplicationTitle
mouseIF

Mol Psychiatry

WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signaling.

Authors - Min Wang
  • KD Validated
humanWB

Oncotarget

TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast.

Authors - Xiaodan Hou
humanWB, IF

J Biol Chem

Phosphatidylinositol 3-kinase and Rab5 GTPase inversely regulate the Smad anchor for receptor activation (SARA) protein independently of transforming growth factor-β1.

Authors - Runyan Constance E CE
mouseWB

Stem Cell Reports

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.

Authors - Xuanmao Jiao