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ZIC1 Polyklonaler Antikörper

ZIC1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 25004-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using ZIC1 Polyclonal antibody (25004-1-AP)

    WB analysis using 25004-1-AP (same clone as 25004-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25004-1-AP (ZIC1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25004-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Y79 cells using ZIC1 Polyclonal antibody (25004-1-AP)

    WB analysis of Y79 using 25004-1-AP (same clone as 25004-1-PBS)

    Y79 cells were subjected to SDS PAGE followed by western blot with 25004-1-AP (ZIC1 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25004-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

25004-1-PBS bindet in WB, Indirect ELISA ZIC1 und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZIC1 fusion protein Ag13400
Vollständiger Name Zic family member 1 (odd-paired homolog, Drosophila)
Berechnetes Molekulargewicht 447 aa, 48 kDa
Beobachtetes Molekulargewicht~50 kDa
GenBank-ZugangsnummerBC104848
Gene symbol ZIC1
Gene ID (NCBI) 7545
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZIC1 is a member of the Zinc finger of the cerebellum (ZIC) protein family. In vertebrates, the ZIC gene family plays an important role in neural crest and subsequent cerebellar development. Mutations in ZIC family members have demonstrated that they are essential for proper development of the neural tube, left-right symmetry, and muscle and skeletal development. It has been reported that ZIC1 participates in the regulation of cell proliferation in the dorsal neural tube by inhibition of neural differentiation. Furthermore, ZIC1 is potentially involved in the oncogenesis of undifferentiated nervous system tumors. (PMID:17936758)