ZMPSTE24 Rekombinanter Antikörper

ZMPSTE24 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241288C3

Kat-Nr. : 84547-2-PBS

Synonyme

FACE-1, FACE1, FACE 1, EC:3.4.24.84, CAAX prenyl protease 1 homolog

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  IF Staining of PC-3 using 84547-2-RR (same clone as 84547-2-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed PC-3 cells using ZMPSTE24 antibody (84547-2-RR, Clone: 241288C3 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84547-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84547-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84547-2-RR against Human ZMPSTE24 were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

84547-2-PBS bindet in IF/ICC, Indirect ELISA ZMPSTE24 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: ZMPSTE24 fusion protein Ag33613
• Vollständiger Name: zinc metallopeptidase (STE24 homolog, S. cerevisiae)
• Berechnetes Molekulargewicht: 475 aa, 55 kDa
• GenBank-Zugangsnummer: BC037283
• Gene symbol: ZMPSTE24
• Gene ID (NCBI): 10269
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZMPSTE24(CAAX prenyl protease 1 homolog) gene encodes a zinc metalloproteinase involved in the processing of farnesylated proteins(PubMed: 10373325). The significance of ZMPSTE24 in human disease stems from its role as an enzyme necessary for the correct processing and maturation of lamin A ,an intermediate filament component of the nuclear envelope (PubMed: 16297189).