ZNF280B Polyklonaler Antikörper

ZNF280B Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32519-1-PBS

Synonyme

Zinc finger protein 632, Zinc finger protein 280B, Zinc finger protein 279, Suppressor of hairy wing homolog 2, SUHW2

---

• 

  WB analysis using 32519-1-AP (same clone as 32519-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32519-1-AP (ZNF280B antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32519-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

32519-1-PBS bindet in WB, Indirect ELISA ZNF280B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: ZNF280B fusion protein Ag38544
• Vollständiger Name: zinc finger protein 280B
• Berechnetes Molekulargewicht: 62kDa，543aa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: NM_080764.3
• Gene symbol: ZNF280B
• Gene ID (NCBI): 140883
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZNF280B belongs to the family of zinc finger proteins, a transcription factor that is mainly involved in the regulation of gene expression. In prostate cancer cells, ZNF280B induces p53 nuclear export, leading to subsequent proteasomal degradation. Therefore, ZNF280B has pro-growth and pro-survival functions in prostate cancer cells. In addition to this, ZNF280B has a promotional role in gastric and lung cancer development, and its potential as a tumor therapeutic target can be explored in the future.