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ZNF706 Polyklonaler Antikörper

ZNF706 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32274-1-PBS

Synonyme

HSPC038, PNAS-113, Zinc finger protein 706

Filter:
  • Western Blot (WB) analysis of A431 cells using ZNF706 Polyclonal antibody (32274-1-AP)

    WB analysis of A431 using 32274-1-AP (same clone as 32274-1-PBS)

    A431 cells were subjected to SDS PAGE followed by western blot with 32274-1-AP (ZNF706 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32274-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32274-1-PBS bindet in WB, Indirect ELISA ZNF706 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZNF706 fusion protein Ag37605
Vollständiger Name zinc finger protein 706
Berechnetes Molekulargewicht 76 aa, 8 kDa
Beobachtetes Molekulargewicht12 kDa
GenBank-ZugangsnummerBC015925
Gene symbol ZNF706
Gene ID (NCBI) 51123
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Zinc Finger domains account for 5% of all human proteins and interact with various substrates, such as lipids, DNA, RNA, and post-translational modifications. In addition, zinc finger proteins (ZNFs) are involved in transcriptional regulation, signal transduction, and other cellular processes. Zinc finger protein 706 (ZNF706), encoded by a gene located at chromosome 8q22.3, is a member of the C2H2-type zinc finger transcription factor family, the most abundant transcription factor family encoded by the human genome. And according to the structural analysis of ZNF706, it was definitely predicted to physically bind to DNA through the C-terminal zinc finger domain. In previous studies, it was reported that the expression of ZNF706 is upregulated in gastric cancer and laryngeal cancer. And ZNF706 may be a biomarker for the early diagnosis of rheumatoid arthritis. ZNF706 is a potential oncogene in liver cancer and functions as a ferroptosis regulator by modulating SLC7A11 expression, constituting a potential therapeutic target for HCC (PMID: 38862581).