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ZNF768 Polyklonaler Antikörper

ZNF768 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 33035-1-PBS

Synonyme

Zinc finger protein 768

Filter:
  • Western Blot (WB) analysis of various lysates using ZNF768 Polyclonal antibody (33035-1-AP)

    WB analysis using 33035-1-AP (same clone as 33035-1-PBS)

    HeLa cells lysate was subjected to SDS PAGE followed by western blot with 33035-1-AP (ZNF768 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33035-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

33035-1-PBS bindet in WB, Indirect ELISA ZNF768 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZNF768 fusion protein Ag37794
Vollständiger Name zinc finger protein 768
Berechnetes Molekulargewicht60 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC013760
Gene symbol ZNF768
Gene ID (NCBI) 79724
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Zinc finger protein 768 (ZNF768) is a zinc finger protein that is crucial in linking oncogenic RAS signaling to cellular senescence and proliferation control. It is a transcription factor that associates with euchromatin and promoter regions of many genes in a cell type-specific manner. ZNF768 is required for cell growth and survival, and its depletion induces a strong proliferative and pro-apoptotic response in several cell lines in vitro. ZNF768 is also involved in regulating cell cycle effectors and p53 targets, with its overexpression sufficient to bypass RAS-induced senescence in a p53-dependent manner (PMID: 34404770; 35419475).