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ZSCAN1 Polyklonaler Antikörper

ZSCAN1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32583-1-PBS

Synonyme

Zinc finger and SCAN domain-containing protein 1

Filter:
  • Western Blot (WB) analysis of various lysates using ZSCAN1 Polyclonal antibody (32583-1-AP)

    WB analysis using 32583-1-AP (same clone as 32583-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32583-1-AP (ZSCAN1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32583-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

32583-1-PBS bindet in WB, Indirect ELISA ZSCAN1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen ZSCAN1 fusion protein Ag37955
Vollständiger Name zinc finger and SCAN domain containing 1
Berechnetes Molekulargewicht408 aa, 45 kDa
Beobachtetes Molekulargewicht45 kDa
GenBank-ZugangsnummerNM_182572
Gene symbol ZSCAN1
Gene ID (NCBI) 284312
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZSCAN1 is a transcription factor containing a zinc finger domain and a SCAN domain. ZSCAN1 has been implicated in diverse biological processes. It has been shown to act as a stemness-related tumor suppressor and transcriptional repressor in breast cancer, targeting TAZ to influence cancer progression. Additionally, ZSCAN1 is involved in early embryonic development, where it helps regulate the expression of genes necessary for proper embryogenesis. It also plays a role in the immune response, with anti-ZSCAN1 autoantibodies being identified as potential diagnostic markers for certain syndromes like ROHHAD (PMID: 38339072). According to Human Protein Atlas database, ZSCAN1 is mainly expressed in brain, pituitary gland and testis tissue.