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ZW10 Rekombinanter Antikörper

ZW10 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251397A5

Kat-Nr. : 86726-1-PBS

Synonyme

HZW10

Filter:
  • Western Blot (WB) analysis of various lysates using ZW10 Recombinant monoclonal antibody (86726-1-RR)

    WB analysis using 86726-1-RR (same clone as 86726-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86726-1-RR (ZW10 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86726-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

86726-1-PBS bindet in WB, Indirect ELISA ZW10 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen ZW10 fusion protein Ag19138
Vollständiger Name ZW10, kinetochore associated, homolog (Drosophila)
Berechnetes Molekulargewicht 779 aa, 89 kDa
Beobachtetes Molekulargewicht 88 kDa
GenBank-ZugangsnummerBC128264
Gene symbol ZW10
Gene ID (NCBI) 9183
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ZW10 is the human homolog of the Drosophila melanogaster Zw10 protein. ZW10 is localized to kinetochores and kinetochore-associated microtubules and is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis(PMID: 17102640). ZW10 proteins in Drosophila and HeLa cells display a similar and intriguing cell cycle-dependent intracellular distribution. ZW10 protein first becomes localized to the kinetochore at prometaphase, but then appears to move onto the kinetochore microtubules of the spindle at metaphase, and then back to the kinetochore at anaphase(PMID: 9700164).