Zinc Alpha 2 Glycoprotein Monoklonaler Antikörper

Zinc Alpha 2 Glycoprotein Monoklonal Antikörper für WB, IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4B8A4

Kat-Nr. : 66178-1-PBS

Synonyme

AZGP1, Zinc-alpha-2-glycoprotein, 4B8A4, ZA2G, ZAG

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  WB analysis of human plasma using 66178-1-Ig (same clone as 66178-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 66178-1-Ig (AZGP1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate hyperplasia using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human prostate hyperplasia using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate hyperplasia tissue slide using 66178-1-Ig (AZGP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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  IF Staining of human breast cancer using 66178-1-Ig (same clone as 66178-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed human breast cancer tissue using Zinc Alpha 2 Glycoprotein antibody (66178-1-Ig, Clone: 4B8A4 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66178-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

66178-1-PBS bindet in WB, IHC, IF-P, Indirect ELISA Zinc Alpha 2 Glycoprotein und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Zinc Alpha 2 Glycoprotein fusion protein Ag5661
• Vollständiger Name: alpha-2-glycoprotein 1, zinc-binding
• Berechnetes Molekulargewicht: 298 aa, 34 kDa
• Beobachtetes Molekulargewicht: 41 kDa
• GenBank-Zugangsnummer: BC033830
• Gene symbol: Zinc Alpha 2 Glycoprotein
• Gene ID (NCBI): 563
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Zinc-alpha-2-glycoprotein (AZGP1), a 41-kDa soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract, and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427).