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c-MYC Monoklonaler Antikörper

c-MYC Monoklonal Antikörper für FC (Intra)

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IF, FC (Intra)

Konjugation

CoraLite® Plus 488 Fluorescent Dye

Publikationen(2)

CloneNo.

3D9C12

Kat-Nr. : CL488-67447

Synonyme

MYC, 3D9C12, bHLHe39, c Myc, Class E basic helix-loop-helix protein 39



Geprüfte Anwendungen

Erfolgreiche Detektion in FC (Intra)K-562-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Durchflusszytometrie (FC) (INTRA)FC (INTRA) : 0.80 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

IFSee 1 publications below
FCSee 1 publications below

Produktinformation

CL488-67447 bindet in IF, FC (Intra) c-MYC und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte ReaktivitätMaus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen c-MYC fusion protein Ag17519
Vollständiger Name v-myc myelocytomatosis viral oncogene homolog (avian)
Berechnetes Molekulargewicht 49 kDa
Beobachtetes Molekulargewicht 55-60 kDa
GenBank-ZugangsnummerBC000141
Gene symbol MYC
Gene ID (NCBI) 4609
Konjugation CoraLite® Plus 488 Fluorescent Dye
Excitation/Emission maxima wavelengths493 nm / 522 nm
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
LagerungsbedingungenBei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

MYC contains one basic helix-loop-helix (bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
FC protocol for CL Plus 488 c-MYC antibody CL488-67447Download protocol
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
mouseFC

Int Immunopharmacol

Oxymatrine inhibits melanoma development by modulating the immune microenvironment and targeting the MYC/PD-L1 pathway

Authors - Xin Li
IF

Nat Commun

Hippo signaling pathway regulates Ebola virus transcription and egress

Authors - Jingjing Liang

Rezensionen

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.


FH

Lisa (Verified Customer) (04-03-2025)

AB gives a nice signal in GC B cells compared to non-GC B cells

  • Applications: Flow Cytometry
  • Primary Antibody Dilution: 1:125
  • Cell Tissue Type: splenocytes