human IgM Monoklonaler Antikörper

human IgM Monoklonal Antikörper für WB, IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2D10B10

Kat-Nr. : 66484-1-PBS

Synonyme

IGHM, IgM, 2D10B10, MU, VH



Geprüfte Anwendungen

Produktinformation

66484-1-PBS bindet in WB, IHC, IF-P, Indirect ELISA human IgM und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen human IgM fusion protein Ag1459
Vollständiger Name immunoglobulin heavy constant mu
Berechnetes Molekulargewicht 69 kDa
Beobachtetes Molekulargewicht 75 kDa
GenBank-ZugangsnummerBC009851
Gene symbol IGHM
Gene ID (NCBI) 3507
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

IGHM is the constant region of heavy chain of IgM. IgM is the first immunoglobulin expressed during B cell development. IgM antibodies play an important role in primary immune response involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The μ heavy chain disease is a rare lymphoproliferative disorder. Human immunoglobulin heavy chain locus translocations are associated with leukaemias and lymphomas, including multiple myeloma, mantle cell lymphoma, Burkitt's lymphoma and diffuse large B cell lymphoma. This antibody detects the heavy chain of human IgM (~75 kDa).