5-methylcytosine Monoklonaler Antikörper

5-methylcytosine Monoklonal Antikörper für IHC, Dot Blot, ELISA, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

m5C

Anwendung

IHC, Dot Blot, ELISA, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2C9G9

Kat-Nr. : 68301-1-PBS

Synonyme

m5C, RNA methylation, 5mC



Geprüfte Anwendungen

Produktinformation

68301-1-PBS bindet in IHC, Dot Blot, ELISA, Indirect ELISA 5-methylcytosine und zeigt Reaktivität mit m5C

Getestete Reaktivität m5C
Wirt / Isotyp Maus / IgG2b
Klonalität Monoklonal
Typ Antikörper
Immunogen Verbindung
Vollständiger Name 5-methylcytosine
Gene symbol
Gene ID (NCBI)
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

In eukaryotes, 5-methylcytosine in DNA (5mC) and its oxidized derivatives (5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC)) are the most prominent modifications and have been suggested to contribute to epigenetic gene regulation through a variety of different mechanisms. m5C has also been found in mRNA, rRNA and tRNA of representative organisms from all kinds of species. As reversible epigenetic modifications, m5C modifications of RNA affect the fate of the modified RNA molecules and play important roles in various biological processes including RNA stability control, protein synthesis, and transcriptional regulation (PMID: 35365216). This antibody can recognize both 5mC in DNA and m5C in RNA.

Protocol for Dot Blot:
https://www.ptglab.com/protocol/68301-1-IgDotBlot.pdf