p38 MAPK Polyklonaler Antikörper
p38 MAPK Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 30382-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
30382-1-PBS bindet in WB, IF/ICC, Indirect ELISA p38 MAPK und zeigt Reaktivität mit human, Maus, Ratten
| Getestete Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | p38 MAPK fusion protein Ag33174 |
| Vollständiger Name | mitogen-activated protein kinase 14 |
| Berechnetes Molekulargewicht | 360 aa, 41 kDa |
| Beobachtetes Molekulargewicht | 38-42 kDa |
| GenBank-Zugangsnummer | BC031574 |
| Gene symbol | p38 MAPK |
| Gene ID (NCBI) | 1432 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation(PMID:22231518). It plays an important role in the regulation of hematopoietic stem cell self-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell(PMID:21198398). This protein has 4 isoforms produced by alternative splicing.



