phospho-RCC1(Ser11) Monoklonaler Antikörper

phospho-RCC1(Ser11) Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG3

Getestete Reaktivität

human, Maus

Anwendung

ELISA

Konjugation

Unkonjugiert

CloneNo.

5G9D8

Kat-Nr. : 60089-1-Ig

Synonyme

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  IHC staining of human testis using 60089-1-Ig

  Immunohistochemical analysis of paraffin-embedded human testis using 60089-1-Ig(phospho-RCC1(Ser12) antibody) at dilution of 1:50 (under 10x lens).

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  IHC staining of human testis using 60089-1-Ig

  Immunohistochemical analysis of paraffin-embedded human testis using 60089-1-Ig(phospho-RCC1(Ser12) antibody) at dilution of 1:50 (under 40x lens).

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  IHC staining of human ovary tumor using 60089-1-Ig

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 60089-1-Ig(phospho-RCC1(Ser12) antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human ovary tumor using 60089-1-Ig

  Immunohistochemical analysis of paraffin-embedded human ovary tumor using 60089-1-Ig(phospho-RCC1(Ser12) antibody) at dilution of 1:50 (under 40x lens).

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Geprüfte Anwendungen

Produktinformation

60089-1-Ig bindet in ELISA phospho-RCC1(Ser11) und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG3
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: regulator of chromosome condensation 1
• Berechnetes Molekulargewicht: 48 kDa
• Beobachtetes Molekulargewicht: 47 kDa
• GenBank-Zugangsnummer: NM_001048194
• Gene symbol: RCC1
• Gene ID (NCBI): 1104
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a mouse monoclonal antibody raised against human phospho-CHC1(Ser11) antigen.