Anticorps Recombinant de lapin anti-A2BP1

A2BP1 Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243149B4

N° de cat : 85732-2-PBS

Synonymes

FOX1, RBFOX1, A2BP, Ataxin-2-binding protein 1, Fox-1 homolog A

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Galerie de données de validation

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  WB analysis using 85732-2-RR (same clone as 85732-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85732-2-RR (A2BP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85732-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP02075-1

  Cytometric bead array standard curve of MP02075-1, A2BP1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 85732-2-PBS. Detection antibody: 85732-4-PBS. Standard: Ag18527. Range: 0.469-60 ng/mL.

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  Affinity and Kinetic Characterization of 85732-2-RR

  Biolayer interferometry (BLl) kinetic assays of 85732-2-RR against Human A2BP1 were performed. The affinity constant is 2.82 nM.

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Informations sur le produit

85732-2-PBS cible A2BP1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: A2BP1 Protéine recombinante Ag18527
• Nom complet: ataxin 2-binding protein 1
• Masse moléculaire calculée: 395 aa, 42 kDa
• Poids moléculaire observé: 45-60 kDa
• Numéro d’acquisition GenBank: BC113691
• Symbole du gène: A2BP1
• Identification du gène (NCBI): 54715
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

A2BP1, also named as FOX1 and HRNBP1, contains one RRM (RNA recognition motif) domain. A2BP1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. A2BP1 and ataxin-2 are both localized in the trans-Golgi network.

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