Anticorps Polyclonal de lapin anti-AADAT

AADAT Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13031-1-PBS

Synonymes

2 aminoadipate transaminase, 2-aminoadipate aminotransferase, 2-aminoadipate transaminase, Alpha-aminoadipate aminotransferase, aminoadipate aminotransferase

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Galerie de données de validation

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  IHC staining of mouse cerebellum using 13031-1-AP (same clone as 13031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 13031-1-AP (AADAT antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 13031-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13031-1-AP (same clone as 13031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer using 13031-1-AP (AADAT antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13031-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 13031-1-AP (same clone as 13031-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer using 13031-1-AP (AADAT antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13031-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13031-1-PBS cible AADAT dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AADAT Protéine recombinante Ag3676
• Nom complet: aminoadipate aminotransferase
• Masse moléculaire calculée: 429 aa, 48 kDa
• Numéro d’acquisition GenBank: BC031068
• Symbole du gène: AADAT
• Identification du gène (NCBI): 51166
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AADAT (alpha-aminoadipate aminotransferase), also known as KAT (kynurenine aminotransferase) II, is a primary enzyme in the brain for catalysing the transamination of kynurenine to KYNA (kynurenic acid). KYNA is the only known endogenous antagonist of the N-methyl-D-aspartate receptor. AADAT is also involved in lysine metabolism by catalyzing the transamination of aminoadipate to a-ketoadipate (PMID: 17024659, 18056995). The human AADAT enzyme is also predicted to contain a mitochondrial cleavage signal, suggesting that AADAT is a mitochondrial protein (PMID: 19826765).

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