Anticorps Polyclonal de lapin anti-ABCG8

ABCG8 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24453-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 24453-1-AP (same clone as 24453-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24453-1-AP (ABCG8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24453-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

24453-1-PBS cible ABCG8 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ABCG8 Protéine recombinante Ag19879
• Nom complet: ATP-binding cassette, sub-family G (WHITE), member 8
• Masse moléculaire calculée: 673 aa, 76 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC113657
• Symbole du gène: ABCG8
• Identification du gène (NCBI): 64241
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ABCG8(ATP-binding cassette sub-family G member 8) and ABCG5(ATP-binding cassette protein G5) are members of the ABC transporter family and are half-type ABC transporters, which consist of six transmembrane helices and one nucleotide-binding domain. ABCG5 and ABCG8 form a heterodimer (ABCG5/ABCG8). Mutations in either ABCG5 or ABCG8 cause a genetic disorder, sitosterolemia. Patients with sitosterolemia show high plant sterol levels and develop hypercholesterolemia and atherosclerosis at a young age.(PMID: 36839356)

{{ptg:RelatedPrimaryAntibodies}}