Anticorps Polyclonal de lapin anti-ABHD15

• Phare
• Validé par KD/KO

ABHD15 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22526-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse lung using 22526-1-AP (same clone as 22526-1-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 22526-1-AP (ABHD15 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22526-1-PBS in a different storage buffer formulation.

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  WB analysis of Transfected HEK-293 using 22526-1-AP (same clone as 22526-1-PBS)

  Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 22526-1-AP (ABHD15 Antibody) at dilution of 1:700 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22526-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22526-1-PBS cible ABHD15 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ABHD15 Protéine recombinante Ag18334
• Nom complet: abhydrolase domain containing 15
• Masse moléculaire calculée: 468 aa, 52 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC012476
• Symbole du gène: ABHD15
• Identification du gène (NCBI): 116236
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ABHD15 belongs to the α/β-hydrolase superfamily which consists of various lipases, esterases, and proteases that share an α/β fold as a common structural feature. ABHD15 is highly expressed in adipose tissues and is required for the anti-lipolytic action of INS in white adipose tissue (WAT). ABHD15 expression is decreased in humans with obesity and diabetes compared to humans with obesity and normal glucose tolerance, identifying ABHD15 as a potential therapeutic target to mitigate INS resistance (PMID: 29768196).

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