Anticorps Polyclonal de lapin anti-ABI3

ABI3 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16227-1-PBS

Synonymes

SSH3BP3, New molecule including SH3, Nesh, ABI gene family member 3, ABI family, member 3

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Galerie de données de validation

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  WB analysis using 16227-1-AP (same clone as 16227-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16227-1-AP (ABI3 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16227-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 16227-1-AP (same clone as 16227-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 16227-1-AP (ABI3 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16227-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 16227-1-AP (same clone as 16227-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 16227-1-AP (ABI3 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16227-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16227-1-PBS cible ABI3 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ABI3 Protéine recombinante Ag8164
• Nom complet: ABI family, member 3
• Masse moléculaire calculée: 366 aa, 39 kDa
• Poids moléculaire observé: 50 kDa
• Numéro d’acquisition GenBank: BC007780
• Symbole du gène: ABI3
• Identification du gène (NCBI): 51225
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ABI family member 3 belongs to the ABL Interactors (ABI) family of proteins, which also includes ABI1 and ABI2. ABI proteins are a class of cytoplasmic molecular junction proteins originally identified as binding chaperones for Abl kinase. The ABI3 gene is thought to be an important regulator of microglia during Alzheimer's disease (AD), and its S209F variant increases the risk of developing AD. Moreover, ABI3 plays an important role in suppressing tumor growth and progression.

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