Anticorps Polyclonal de lapin anti-ABR

• Phare
• Validé par KD/KO

ABR Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29350-1-PBS

Synonymes

active BCR related gene, MDB

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Galerie de données de validation

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  WB analysis using 29350-1-AP (same clone as 29350-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29350-1-AP (ABR antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29350-1-PBS in a different storage buffer formulation.

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  WB analysis of U-251 using 29350-1-AP (same clone as 29350-1-PBS)

  WB result of ABR antibody (29350-1-AP; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-ABR transfected U-251 cells. This data was developed using the same antibody clone with 29350-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 29350-1-AP (same clone as 29350-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 29350-1-AP (ABR antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29350-1-PBS in a different storage buffer formulation.

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  IHC staining of rat brain using 29350-1-AP (same clone as 29350-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 29350-1-AP (ABR antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29350-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29350-1-PBS cible ABR dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ABR Protéine recombinante Ag29522
• Nom complet: active BCR-related gene
• Masse moléculaire calculée: 98 kDa
• Poids moléculaire observé: 97-100 kDa
• Numéro d’acquisition GenBank: NM_021962
• Symbole du gène: ABR
• Identification du gène (NCBI): 29
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ABR (Active breakpoint cluster region-related protein) is the only protein known in humans and mice to share high homology with BCR (68% amino acid identity). BCR(Breakpoint cluster region) gene was originally identified due to its involvement in a specific chromosomal translocation that causes the development of chronic myeloid leukemia and a subset of acute lymphoblastic leukemia. The C-terminus is a GTPase-activating protein domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. (PMID: 17116687, PMID: 37507586)

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