Anticorps Polyclonal de lapin anti-ACTG2

ACTG2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31849-1-PBS

Synonymes

ACTA3, Actin, gamma-enteric smooth muscle, Actin, gamma-enteric smooth muscle, intermediate form, ACTL3, ACTSG

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Galerie de données de validation

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  WB analysis using 31849-1-AP (same clone as 31849-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31849-1-AP (ACTG2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31849-1-PBS in a different storage buffer formulation.

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  WB analysis using 31849-1-AP (same clone as 31849-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31849-1-AP (ACTG2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31849-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse stomach using 31849-1-AP (same clone as 31849-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 31849-1-AP (ACTG2 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31849-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse stomach using 31849-1-AP (same clone as 31849-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 31849-1-AP (ACTG2 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31849-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31849-1-PBS cible ACTG2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ACTG2 Protéine recombinante Ag36024
• Nom complet: actin, gamma 2, smooth muscle, enteric
• Masse moléculaire calculée: 42 kDa
• Poids moléculaire observé: 42 kDa
• Numéro d’acquisition GenBank: BC094877
• Symbole du gène: ACTG2
• Identification du gène (NCBI): 72
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Actin gamma 2 (ACTG2, also known as ACT, ACTE, VSCM, ACTA3, ACTL3, and ACTSG) is a highly conserved protein involved in various types of cell motility and ubiquitously expressed in all eukaryotic cells. ACTG2 mutations would cause congenital distended bladder, microcolon, and intestinal hypoperistalsis (PMID: 24337657). It also has been reported that ACTG2 promotes hepatocellular carcinoma (HCC) migration and invasion through the Notch1 signaling pathway, which might serve as a new intervention target for the treatment of HCC (PMID: 28385530).

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