Anticorps Recombinant de lapin anti-ACVRL1

ACVRL1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241686H2

N° de cat : 84421-3-PBS

Synonymes

ALK1, ALK 1, ACVRLK1, Activin receptor-like kinase 1, Activin receptor like kinase 1

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Galerie de données de validation

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  WB analysis of HUVEC using 84421-3-RR (same clone as 84421-3-PBS)

  HUVEC cells were subjected to SDS PAGE followed by western blot with 84421-3-RR (ACVRL1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84421-3-PBS in a different storage buffer formulation.

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Informations sur le produit

84421-3-PBS cible ACVRL1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: FusionProtein
• Nom complet: activin A receptor type II-like 1
• Masse moléculaire calculée: 56 kDa
• Poids moléculaire observé: 63 kDa
• Numéro d’acquisition GenBank: BC042637
• Symbole du gène: ACVRL1
• Identification du gène (NCBI): 94
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ACVRL1 (ALK1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. ACVRL1 is highly expressed in endothelial cells and has a critical role in the control of blood vessel development and repair (PMID: 8640225). Mutations in the ACVRL1 gene are associated with hemorrhagic telangiectasia type 2.

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