Anticorps Polyclonal de lapin anti-ADAM11

ADAM11 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32970-1-PBS

Synonymes

ADAM 11, Disintegrin and metalloproteinase domain-containing protein 11, MDC, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein

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Galerie de données de validation

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  WB analysis using 32970-1-AP (same clone as 32970-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32970-1-AP (ADAM11 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32970-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32970-1-PBS cible ADAM11 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ADAM11 Protéine recombinante Ag35877
• Nom complet: ADAM metallopeptidase domain 11
• Masse moléculaire calculée: 83kDa
• Poids moléculaire observé: 83 kDa
• Numéro d’acquisition GenBank: NM_001318933
• Symbole du gène: ADAM11
• Identification du gène (NCBI): 4185
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ADAM11 (A Disintegrin And Metalloprotease 11) is a non-catalytic, transmembrane member of the ADAM family. Although it retains the prototypical multi-domain architecture (signal peptide ‑ pro‑domain ‑ metalloprotease-like ‑ disintegrin ‑ cysteine-rich ‑ EGF-like ‑ TM ‑ cytoplasmic tail), it lacks the consensus HEXGHXXGXXHD zinc-binding motif, rendering it proteolytically inactive . Instead, ADAM11 functions as a cell-adhesion and signalling scaffold. (PMID: 31236626)

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