Anticorps Polyclonal de lapin anti-ADAM2

ADAM2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 13952-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis of mouse testis using 13952-1-AP (same clone as 13952-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13952-1-AP (ADAM2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13952-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 13952-1-AP (same clone as 13952-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13952-1-AP (ADAM2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13952-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse testis using 13952-1-AP (same clone as 13952-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 13952-1-AP (ADAM2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13952-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human testis using 13952-1-AP (same clone as 13952-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 13952-1-AP (ADAM2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13952-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

13952-1-PBS cible ADAM2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ADAM2 Protéine recombinante Ag5063
• Nom complet: ADAM metallopeptidase domain 2
• Masse moléculaire calculée: 82 kDa
• Poids moléculaire observé: 50-55 kDa, 65-75 kDa
• Numéro d’acquisition GenBank: BC034957
• Symbole du gène: ADAM2
• Identification du gène (NCBI): 2515
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The members of the ADAM (a disintegrin and metalloprotease) family are membrane-anchored multi-domain proteins that play prominent roles in male reproduction(PMID: 27341348). Fertilin, a heterodimeric protein complex composed of a(ADAM1) and b(ADAM2) subunits present on the sperm surface, has been believed to mediate adhesion and fusion between the sperm and egg plasma membranes. ADAM2-deficient mouse sperm is also defective in adhesion to and fusion with the egg membrane (PMID:16407235). It has 2 isoforms produced by alternative splicing and 5 glycosylation sites.

{{ptg:RelatedPrimaryAntibodies}}