Anticorps Polyclonal de lapin anti-ADAM23

ADAM23 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32969-1-PBS

Synonymes

ADAM 23, Disintegrin and metalloproteinase domain-containing protein 23, MDC3, MDC-3, Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3

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Galerie de données de validation

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  WB analysis using 32969-1-AP (same clone as 32969-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32969-1-AP (ADAM23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32969-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 32969-1-AP (same clone as 32969-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32969-1-AP (ADAM23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32969-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32969-1-PBS cible ADAM23 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ADAM23 Protéine recombinante Ag35744
• Nom complet: ADAM metallopeptidase domain 23
• Masse moléculaire calculée: 832 aa, 92 kDa
• Poids moléculaire observé: 92 kDa, 70 kDa
• Numéro d’acquisition GenBank: BC132765
• Symbole du gène: ADAM23
• Identification du gène (NCBI): 8745
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ADAM23 (A disintegrin and metalloprotease protein 23), also known as MDC-3 (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3) is a transmembrane type I glycoprotein involved with the development and maintenance of the nervous system, including neurite outgrowth, neuronal adhesion and differentiation and regulation of synaptic transmission. In addition, ADAM23 seems to participate in immune response and tumor establishment through interaction with different members of integrin receptors (PMID: 19692335). Two forms of ADAM23 have been previously described in primary cerebellar granule cells as an unprocessed precursor (100 kDa) and mature (70 kDa) protein, respectively (PMID: 29792904).

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