Anticorps Polyclonal de lapin anti-ADCY8

• Phare
• Validé par KD/KO

ADCY8 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris et plus (1)

Applications

WB, IF, ELISA

Conjugaison

Non conjugué

Publications(5)

N° de cat : 55065-1-AP

Synonymes

AC8, ADCY3, ADCY8, adenylate cyclase 8 (brain), Adenylate cyclase type 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, ATP pyrophosphate lyase 8, HBAC1

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Galerie de données de validation

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  WB analysis of Neuro-2a using 55065-1-AP

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 55065-1-AP (ADCY8 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of Neuro-2a using 55065-1-AP

  Neuro-2a cells were subjected to SDS PAGE followed by western blot with 55065-1-AP (ADCY8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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  WB analysis of SH-SY5Y using 55065-1-AP

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 55065-1-AP (ADCY8 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules Neuro-2a, cellules SH-SY5Y

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 4 publications below
• IF: See 2 publications below

Informations sur le produit

55065-1-AP cible ADCY8 dans les applications de WB, IF, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Réactivité citée: rat, Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: adenylate cyclase 8 (brain)
• Masse moléculaire calculée: 140 kDa
• Poids moléculaire observé: 140-150 kDa
• Numéro d’acquisition GenBank: NM_001115
• Symbole du gène: ADCY8
• Identification du gène (NCBI): 114
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20 ℃. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

ADCY8 Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence. The antibody is specific to ADCY8.

Publications

Species	Application	Title
human	IF	Phytochemistry; Hypoglycemic flavonoids from Selaginella tamariscina (P.Beauv.) Spring.; Authors - Hong-Ping Long
human	WB	Function (Oxf); AKAP79 Orchestrates a Cyclic AMP Signalosome Adjacent to Orai1 Ca2+ Channels.; Authors - Pulak Kar
human	WB	Nat Commun; A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.; Authors - Xuexin Zhang ; KD Validated
rat	WB,IF	Mol Ther; Inhibition of adenylyl cyclase 8 prevents the upregulation of Orai1 channel which improves cardiac function after myocardial infarction; Authors - Débora Falcón
	WB	Int J Mol Sci; Combined Proteomic and Metabolomic Analysis Reveals Comprehensive Regulation of Somatostatin DNA Vaccine in Goats; Authors - Ge Qin

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