Anticorps Recombinant de lapin anti-Adiponectin

Adiponectin Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241082C11

N° de cat : 83961-1-PBS

Synonymes

ADIPOQ, 241082C11, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein

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Galerie de données de validation

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  IF Staining of 3T3-L1 using 83961-1-RR (same clone as 83961-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed 3T3-L1 cells using Adiponectin antibody (83961-1-RR, Clone: 241082C11 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83961-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83961-1-RR

  Biolayer interferometry (BLl) kinetic assays of 83961-1-RR against Human Adiponectin were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83961-1-PBS cible Adiponectin dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Adiponectin Protéine recombinante Ag16304
• Nom complet: adiponectin, C1Q and collagen domain containing
• Masse moléculaire calculée: 244 aa, 26 kDa
• Numéro d’acquisition GenBank: BC096308
• Symbole du gène: Adiponectin
• Identification du gène (NCBI): 9370
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Adiponectin (AdipoQ), an adipocyte-derived hormone, is one of the most abundant adipokines in the blood circulation. Adiponectin modulates a number of metabolic processes, including improving INS sensitivity and anti-inflammatory activity. The role of AdipoQ in reproduction is not yet fully understood, but the expression of AdipoQ in reproductive tissues has been observed in various animals and humans, including chicken testis, bovine ovary, and human placenta. Adiponectin exerts its effects by activating a range of different signaling molecules via binding to two transmembrane AdipoQ receptors, AdipoR1 and AdipoR2. AdipoR1 is expressed primarily in the skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoQ May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors.

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