Anticorps Polyclonal de lapin anti-ADPRM

ADPRM Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17017-1-PBS

Synonymes

C17orf48, ADPRibase Mn, ADPRibase-Mn, ADP-Ribose/CDP-Alcohol Diphosphatase, Manganese Dependent, CDP choline phosphohydrolase

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Galerie de données de validation

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  WB analysis using 17017-1-AP (same clone as 17017-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17017-1-AP (C17orf48 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17017-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17017-1-PBS cible ADPRM dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ADPRM Protéine recombinante Ag9997
• Nom complet: chromosome 17 open reading frame 48
• Masse moléculaire calculée: 40 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC001294
• Symbole du gène: C17orf48
• Identification du gène (NCBI): 56985
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ADPRM (ADP-ribose/CDP-alcohol diphosphatase, manganese dependent) is a manganese-dependent glycophosphatase primarily responsible for the breakdown of molecules such as ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine in the cell. The protein is predicted to be located in the cytoplasm and possesses 2',3'-cyclic nucleotide 2'-phosphodiesterase activity, manganese ion-binding activity, and pyrophosphatase activity. ADPRM plays an important role in embryonic development, particularly in the formation of the heart and lungs. In addition, ADPRM may be involved in immune cell signaling, acting as a second messenger for ADP-ribose to activate TRPM2, which in turn regulates oxidative/nitrosative stress.

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