Anticorps Polyclonal de lapin anti-ADRB1

ADRB1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28323-1-PBS

Synonymes

ADRB1R, B1AR, Beta 1 adrenergic receptor

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Galerie de données de validation

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  WB analysis using 28323-1-AP (same clone as 28323-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 28323-1-AP (ADRB1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28323-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse lung using 28323-1-AP (same clone as 28323-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse lung tissue slide using 28323-1-AP (ADRB1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28323-1-PBS in a different storage buffer formulation.

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Informations sur le produit

28323-1-PBS cible ADRB1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ADRB1 Protéine recombinante Ag28223
• Nom complet: adrenergic, beta-1-, receptor
• Masse moléculaire calculée: 51 kDa
• Poids moléculaire observé: 49 kDa
• Numéro d’acquisition GenBank: NM_000684
• Symbole du gène: ADRB1
• Identification du gène (NCBI): 153
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ADRB1 (adrenergic receptor beta 1), a member of the G protein-coupled receptor (GPCR) superfamily, responds to catecholamine stimulation. ADRB1 is the predominant subtype expressed in the heart and mediates increases in inotropy and chronotropy when stimulated. ADRB1 mediates a wide range of cardiovascular physiological responses and has been of great interest to researchers as a therapeutic target for cardiovascular diseases. Moreover, three subtypes of ADRBs (ADRB1, ADRB2, and ADRB3) are encoded by three separate genes (PMID:16636683; 33372534; 33593484).

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