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Anticorps Polyclonal de lapin anti-ADRB2

ADRB2 Polyclonal Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29864-1-PBS

Synonymes

ADRB2R, ADRBR, B2AR, BAR, Beta 2 adrenergic receptor

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using ADRB2 Polyclonal antibody (29864-1-AP)

    WB analysis using 29864-1-AP (same clone as 29864-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 29864-1-AP (ADRB2 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29864-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using ADRB2 Polyclonal antibody (29864-1-AP)

    WB analysis using 29864-1-AP (same clone as 29864-1-PBS)

    A549 cells were subjected to SDS PAGE followed by western blot with 29864-1-AP (ADRB2 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29864-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse stomach tissue using ADRB2 Polyclonal antibody (29864-1-AP)

    IF Staining of mouse stomach using 29864-1-AP (same clone as 29864-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse stomach tissue using ADRB2 antibody (29864-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29864-1-PBS in a different storage buffer formulation.

Informations sur le produit

29864-1-PBS cible ADRB2 dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène ADRB2 Protéine recombinante Ag32313
Nom complet adrenergic, beta-2-, receptor, surface
Masse moléculaire calculée46 kDa
Poids moléculaire observé46-48 kDa
Numéro d’acquisition GenBankBC012481
Symbole du gène ADRB2
Identification du gène (NCBI) 154
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Beta-2 adrenergic receptor (ADRB2), a member of the G protein-coupled receptor (GPCR) family, binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. ADRB2 is directly linked to one of its final effectors, the class C L-type Ca2+ channel, Cav1.2 (PMID: 11441182). This receptor-channel complex also contains a G protein, an adenylyl cyclase, cyclic adenosine monophosphate-dependent protein kinase (PKA), and a counteracting phosphatase, PP2A. Different polymorphic forms, point mutations, and/or downregulation of the gene of ADRB2 are associated with nocturnal asthma, obesity, and type 2 diabetes. This antibody detects ADRB2 with a molecular weight of 46-48 kDa as has been shown by some researches (PMID: 30542705; 35075132).

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