Anticorps Polyclonal de lapin anti-ADRB3

ADRB3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30713-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 30713-1-AP (same clone as 30713-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30713-1-AP (ADRB3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30713-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30713-1-PBS cible ADRB3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: ADRB3 Protéine recombinante Ag31466
• Nom complet: adrenergic, beta-3-, receptor
• Masse moléculaire calculée: 44 kDa
• Poids moléculaire observé: 44-50 kDa
• Numéro d’acquisition GenBank: NM_000025
• Symbole du gène: ADRB3
• Identification du gène (NCBI): 155
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Beta-3 adrenergic receptor(ADRB3), a member of the G-protein-coupled receptor family, is expressed mainly in adipose tissue and is thought to contribute to lipolysis and thermogenesis. In addition, the overexpression of ADRB3 has been found in several cancer types, including breast cancer, gallbladder cancer , and colorectal cancer. More recently, the involvement of ADRB3 in the metabolic reprogramming of melanoma, the promotion of immune tolerance, and the regulation of cancer differentiation have been described. (PMID: 32514619)

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