Anticorps Polyclonal de lapin anti-AES

AES Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 23913-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 23913-1-AP (same clone as 23913-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 23913-1-AP (AES antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 23913-1-PBS in a different storage buffer formulation.

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Informations sur le produit

23913-1-PBS cible AES dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AES Protéine recombinante Ag21021
• Nom complet: amino-terminal enhancer of split
• Masse moléculaire calculée: 264 aa, 29 kDa
• Poids moléculaire observé: 22-29 kDa
• Numéro d’acquisition GenBank: BC113735
• Symbole du gène: AES
• Identification du gène (NCBI): 166
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Amino-terminal enhancer of split (AES), belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members in order to forcefully repress the expression of other family member genes. AES can repress NFkB-regulated gene expression and is believed to have a significant role in initiating and maintaining cell differentiation events. AES has been found to suppress local invasion and intravasation through inhibition of the Notch pathway, leading to preventing the metastatic spread of endogenous tumors(PMID: 33754069).

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