Anticorps Polyclonal de lapin anti-AGA

AGA Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17299-1-PBS

Synonymes

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Galerie de données de validation

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  IHC staining of mouse kidney using 17299-1-AP (same clone as 17299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17299-1-AP (AGA antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17299-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 17299-1-AP (same clone as 17299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 17299-1-AP (AGA antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17299-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17299-1-AP (same clone as 17299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17299-1-AP (AGA Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 17299-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 17299-1-AP (same clone as 17299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 17299-1-AP (AGA Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 17299-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17299-1-PBS cible AGA dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AGA Protéine recombinante Ag10681
• Nom complet: aspartylglucosaminidase
• Masse moléculaire calculée: 346 aa, 37 kDa
• Numéro d’acquisition GenBank: BC012392
• Symbole du gène: AGA
• Identification du gène (NCBI): 175
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AGA(Aspartylglucosaminidase) is also named as N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase and glycosylasparaginase.The open reading frame of the readthrough transcript would indicate AGA close to 40 kDa.It can be cleaved into 2 chains:the 24 kDa α- and 17 kDa β-subunits of the wild-type AGA,in addition,an aberrant polypeptide with a mol.wt of 21 kDa is also detected as a product of proteolytic cleavage of the mutant precursor molecule(PMID: 9425233).AGA can exsit as a dimer with the mol.wt between 100 kDa and 49 kDa and His124 at an interface between two heterodimers of AGA is crucial for the thermodynamically stable oligomeric structure of AGA.(PMID:9737998). It can also exsit as a heterotetrameric protein of 88 kDa(PMID:1733831).

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