Anticorps Polyclonal de lapin anti-AGGF1

• Phare
• Validé par KD/KO

AGGF1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11889-1-PBS

Synonymes

HUS84971, HSU84971, GPATCH7, GPATC7, G patch domain-containing protein 7

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Galerie de données de validation

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  WB analysis using 11889-1-AP (same clone as 11889-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11889-1-AP (AGGF1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11889-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 11889-1-AP (same clone as 11889-1-PBS)

  WB result of AGGF1 antibody (11889-1-AP; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-AGGF1 transfected HeLa cells. This data was developed using the same antibody clone with 11889-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11889-1-PBS cible AGGF1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AGGF1 Protéine recombinante Ag2497
• Nom complet: angiogenic factor with G patch and FHA domains 1
• Masse moléculaire calculée: 714 aa, 81 kDa
• Poids moléculaire observé: 84-100 kDa
• Numéro d’acquisition GenBank: BC029382
• Symbole du gène: AGGF1
• Identification du gène (NCBI): 55109
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.

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