Anticorps Recombinant de lapin anti-AGGF1

AGGF1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242264E9

N° de cat : 84715-3-PBS

Synonymes

242264E9, Angiogenic factor VG5Q, G patch domain-containing protein 7, GPATC7, GPATCH7

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Galerie de données de validation

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  WB analysis using 84715-3-RR (same clone as 84715-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84715-3-RR (AGGF1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84715-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84715-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84715-3-RR against Human AGGF1 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

84715-3-PBS cible AGGF1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: AGGF1 Protéine recombinante Ag2497
• Nom complet: angiogenic factor with G patch and FHA domains 1
• Masse moléculaire calculée: 714 aa, 81 kDa
• Poids moléculaire observé: 84-100 kDa
• Numéro d’acquisition GenBank: BC029382
• Symbole du gène: AGGF1
• Identification du gène (NCBI): 55109
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.

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