Anticorps Polyclonal de lapin anti-AGXT

AGXT Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 22394-1-PBS

Synonymes

EC:2.6.1.51, EC:2.6.1.44, Alanine--glyoxylate aminotransferase, AGXT1, AGT1

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Galerie de données de validation

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  WB analysis of mouse liver using 22394-1-AP (same clone as 22394-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 22394-1-AP (AGXT antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22394-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse lung using 22394-1-AP (same clone as 22394-1-PBS)

  mouse lung tissue were subjected to SDS PAGE followed by western blot with 22394-1-AP (AGXT antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22394-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 22394-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver slide using 22394-1-AP (AGXT Antibody) at dilution of 1:50.

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  IHC staining of human liver using 22394-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver slide using 22394-1-AP (AGXT Antibody) at dilution of 1:50.

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Informations sur le produit

22394-1-PBS cible AGXT dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AGXT Protéine recombinante Ag18062
• Nom complet: alanine-glyoxylate aminotransferase
• Masse moléculaire calculée: 392 aa, 43 kDa
• Poids moléculaire observé: 43-45 kDa
• Numéro d’acquisition GenBank: BC132819
• Symbole du gène: AGXT
• Identification du gène (NCBI): 189
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AGXT (AGT) is a key enzyme in glyoxylate detoxification. Mutations of AGXT lead to primary hyperoxaluria type I, a rare metabolic disease that is characterized by deficient AGXT, and excessive hepatic oxalate production that leads to renal failure.

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