Anticorps Recombinant de lapin anti-AGXT2L1

AGXT2L1 Recombinant Antibody for IHC, IF/ICC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IHC, IF/ICC, ELISA

Conjugaison

Non conjugué

CloneNo.

241119H5

N° de cat : 83984-5-PBS

Synonymes

ETNPPL, Ethanolamine-phosphate phospho-lyase, EC:4.2.3.2, Alanine--glyoxylate aminotransferase 2-like 1, 241119H5

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Galerie de données de validation

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  IHC staining of mouse liver using 83984-5-RR (same clone as 83984-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83984-5-RR (AGXT2L1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 83984-5-RR (same clone as 83984-5-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 83984-5-RR (AGXT2L1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  IF Staining of U2OS using 83984-5-RR (same clone as 83984-5-PBS)

  Immunofluorescent analysis of (4% PFA) fixed U2OS cells using AGXT2L1 antibody (83984-5-RR, Clone: 241119H5 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 83984-5-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83984-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83984-5-RR against Human AGXT2L1 were performed. The affinity constant is 1.77 nM.

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Informations sur le produit

83984-5-PBS cible AGXT2L1 dans les applications de IHC, IF/ICC, ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: AGXT2L1 Protéine recombinante Ag10584
• Nom complet: alanine-glyoxylate aminotransferase 2-like 1
• Masse moléculaire calculée: 499 aa, 56 kDa
• Numéro d’acquisition GenBank: BC022526
• Symbole du gène: AGXT2L1
• Identification du gène (NCBI): 64850
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768,

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