Anticorps Recombinant de lapin anti-AGXT2L1

AGXT2L1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241119C4

N° de cat : 83984-6-PBS

Synonymes

ETNPPL, Ethanolamine-phosphate phospho-lyase, EC:4.2.3.2, Alanine--glyoxylate aminotransferase 2-like 1, 241119C4

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Galerie de données de validation

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  WB analysis using 83984-6-RR (same clone as 83984-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 83984-6-RR (AGXT2L1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83984-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83984-6-RR

  Biolayer interferometry (BLl) kinetic assays of 83984-6-RR against Human AGXT2L1 were performed. The affinity constant is 5.17 nM.

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Informations sur le produit

83984-6-PBS cible AGXT2L1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: AGXT2L1 Protéine recombinante Ag10584
• Nom complet: alanine-glyoxylate aminotransferase 2-like 1
• Masse moléculaire calculée: 499 aa, 56 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC022526
• Symbole du gène: AGXT2L1
• Identification du gène (NCBI): 64850
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Alanine-glyoxylate aminotransferase 2-like 1 (AGXT2L1), also called ethanolamine phosphate phospholyase (ETNPPL), is a brain enzyme, so-named after its similarity to AGXT2 (36% sequence identity), that may be involved in the pathogenesis of severe neuropsychiatric disturbances(PMID: 23761375). AGXT2L1 is significantly down-regulated in cancerous tissues and may be a tumor suppressor(PMID: 26294768).

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