Anticorps Polyclonal de lapin anti-AK6

AK6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30517-1-PBS

Synonymes

Adenylate kinase isoenzyme 6, CINAP, KAD6

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Galerie de données de validation

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  WB analysis using 30517-1-AP (same clone as 30517-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30517-1-AP (AK6 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30517-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 30517-1-AP (same clone as 30517-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 30517-1-AP (AK6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30517-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30517-1-PBS cible AK6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AK6 Protéine recombinante Ag29330
• Nom complet: AK6
• Masse moléculaire calculée: 20 kDa
• Poids moléculaire observé: 20-24 kDa
• Numéro d’acquisition GenBank: NM_016283.4
• Symbole du gène: AK6
• Identification du gène (NCBI): 102157402
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Adenylate Kinase 6 (AK6), also known as human coilin-interacting nuclear ATPase protein (hCINAP), is a unique enzyme that belongs to the adenylate kinase family. It is encoded by the AK6 gene located on chromosome 5q13.2. AK6 is a dual-activity enzyme, possessing both adenylate kinase and ATPase activities. The protein is involved in various biological processes, including gene transcription, ribosome quality control, embryonic development, cellular senescence, metabolism, proliferation, apoptosis, DNA damage response, and inflammation. It is also implicated in tumor development and has been explored as a potential drug target for cancer and neurodegenerative diseases.

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