Anticorps Polyclonal de lapin anti-AKAP8

AKAP8 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31542-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 31542-1-AP (same clone as 31542-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31542-1-AP (AKAP8 antibody) at dilution of 1:15000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31542-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31542-1-PBS cible AKAP8 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AKAP8 Protéine recombinante Ag35816
• Nom complet: A kinase (PRKA) anchor protein 8
• Masse moléculaire calculée: 76kDa，692aa
• Poids moléculaire observé: 95 kDa
• Numéro d’acquisition GenBank: NM_005858.3
• Symbole du gène: AKAP8
• Identification du gène (NCBI): 10270
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

AKAP8 (A-kinase anchor protein 8), also called AKAP95, is a A-kinase anchor protein that directs activity of protein kinase A by tethering the enzyme near its physiologic substrates (PMID: 9473338; 10601332). It is associated with chromatin and nuclear matrix which has a remarkable activity in promoting chromatin transcription (PMID: 31980632), and it is also required for cell cycle G2/M transition and histone deacetylation during mitosis (PMID: 16980585).

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