Anticorps Polyclonal de lapin anti-AKR7A3

AKR7A3 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

Publications(1)

N° de cat : 13209-1-AP

Synonymes

EC:1.-.-.-, AFB1-AR 2, AFB1 AR 2, AFB1 aldehyde reductase 2, AFAR2

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Galerie de données de validation

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  WB analysis of human liver using 13209-1-AP

  human liver tissue were subjected to SDS PAGE followed by western blot with 13209-1-AP (AKR7A3 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

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  WB analysis of HepG2 using 13209-1-AP

  HepG2 cells were subjected to SDS PAGE followed by western blot with 13209-1-AP (AKR7A3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of NIH/3T3 using 13209-1-AP

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 13209-1-AP (AKR7A3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  WB analysis of human brain using 13209-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 13209-1-AP (AKR7A3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu hépatique humain, cellules HepG2, cellules NIH/3T3, tissu cérébral humain

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• WB: See 1 publications below

Informations sur le produit

13209-1-AP cible AKR7A3 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: AKR7A3 Protéine recombinante Ag3991
• Nom complet: aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
• Masse moléculaire calculée: 331 aa, 37 kDa
• Poids moléculaire observé: 37 kDa and 55-60 kDa
• Numéro d’acquisition GenBank: BC025709
• Symbole du gène: AKR7A3
• Identification du gène (NCBI): 22977
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

AKR7A3 belongs to the aldo‐keto reductase (AKR) superfamily, whose primary role is to reduce aldehydes and ketones to generate primary and secondary alcohols, respectively. These enzymes have been shown to play crucial roles in drug metabolism, carcinogen metabolism, and cellular metabolism. Growing evidence suggests that AKR7A3 can play an essential role in the occurrence of cancers, including breast and liver cancers. (PMID: 36951402)

Publications

Species	Application	Title
rat	WB	Toxicol Sci; Generation of A New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity.; Authors - Keiko Taguchi

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