Anticorps Monoclonal anti-ALDH1A1
ALDH1A1 Monoclonal Antibody for ELISA
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain
Applications
ELISA
Conjugaison
Non conjugué
N° de cat : 65004-1-Ig
Synonymes
Galerie de données de validation
Applications testées
Dilution recommandée
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Informations sur le produit
65004-1-Ig cible ALDH1A1 dans les applications de ELISA et montre une réactivité avec des échantillons Humain
| Réactivité | Humain |
| Hôte / Isotype | Mouse / IgG1 |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | Protéine recombinante |
| Nom complet | aldehyde dehydrogenase 1 family, member A1 |
| Masse moléculaire calculée | 501 aa, 55 kDa |
| Poids moléculaire observé | 55 kDa |
| Numéro d’acquisition GenBank | BC001505 |
| Symbole du gène | ALDH1A1 |
| Identification du gène (NCBI) | 216 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine G |
| Tampon de stockage | PBS avec azoture de sodium à 0,1 % et glycérol à 50 % pH 7,3 |
| Conditions de stockage | Stocker à une température comprise entre 2 °C et 8 °C. 20ul contiennent 0,1% de BSA. |
Informations générales
ALDH1A1(Aldehyde dehydrogenase family 1 member A1 ), also named as ALDC, ALDH1 and PUMB1, belongs to the aldehyde dehydrogenase family. The ALDH1A1 gene encodes a liver cytosolic isoform of acetaldehyde dehydrogenase, an enzyme involved in the major pathway of alcohol metabolism after alcohol dehydrogenase. ALDH1A1 plays a critical role in protection against oxidative stress-induced cytotoxicity in lens epithelial cells(PMID:19296407). And it is important for multiple biological activities including drug resistance, cell differentiation, and oxidative stress response(PMID:19025616). As a novel cancer stem cell marker, ALDH1A1 can be used for tumors whose corresponding normal tissues express ALDH1 in relatively restricted or limited levels such as breast, lung, ovarian or colon cancer(PMID: 20422001).
