Anticorps Recombinant de lapin anti-ALDH1B1

ALDH1B1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242944D1

N° de cat : 85426-4-PBS

Synonymes

242944D1, Aldehyde dehydrogenase 5, Aldehyde dehydrogenase X, mitochondrial, ALDH5, ALDHX

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Galerie de données de validation

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  WB analysis using 85426-4-RR (same clone as 85426-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85426-4-RR (ALDH1B1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85426-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85426-4-RR

  Biolayer interferometry (BLl) kinetic assays of 85426-4-RR against Human ALDH1B1 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

85426-4-PBS cible ALDH1B1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: ALDH1B1 Protéine recombinante Ag7144
• Nom complet: aldehyde dehydrogenase 1 family, member B1
• Masse moléculaire calculée: 57 kDa
• Poids moléculaire observé: 55 kDa
• Numéro d’acquisition GenBank: BC001619
• Symbole du gène: ALDH1B1
• Identification du gène (NCBI): 219
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Aldehyde dehydrogenases (ALDHs) belong to a superfamily of NAD(P)+-dependent enzymes, which catalyze the oxidation of endogenous and exogenous aldehydes to their corresponding acids. ALDH1B1 is a mitochondrial ALDH that it is dramatically upregulated in human colonic adenocarcinoma, making it a potential biomarker for human colon cancer.(PMID:21216231). ALDH1B1 is a homotetramer expressed in various adult and fetal human tissues including liver, testis, kidney, skeletal muscle, heart, placenta, brain and lung(PMID:18611112). This antibody is specific to ALDH1B1.

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